Welcome to vnonline.co.uk

vnonline.co.uk provides the veterinary nursing profession with the latest news and industry developments, as well as events, resources, learning materials and careers.

Our website is dedicated to veterinary nurses and we strive to provide a platform where you can voice and explore your interests.

Not a member yet? Sign up for free!

Register for free with vnonline.co.uk to gain unlimited access to news, resources, jobs and much more!



Click here to become a member






Log in to vnonline

Forgot your password?

Posted: 3rd July 2020

Pigs useful for testing influenza antibody treatment, study finds
"We are very excited that the pig model is useful for testing and refining antibody treatments for life-threatening influenza infections" - Dr Elma Tchilian.
Researchers discover human antibody that can neutralise H1N1 swine flu strain.

A human antibody has been proven to protect pigs against the strain of influenza that caused the 2009 H1N1 swine flu pandemic.

The finding by researchers at The Pirbright Institute suggests that the antibody could be effective at treating human influenza infections. It also shows that pigs are a useful model for testing influenza antibody treatments.

Funded by the Bill & Melinda Gates Foundation and the Biotechnology and Biological Sciences Research Council (BBSRC), the study is published in the Journal of Immunology.

“We are very excited that the pig model is useful for testing and refining antibody treatments for life-threatening influenza infections,” commented Dr Elma Tchilian, head of the Mucosal Immunology Group at Pirbright. “I hope that research into many other infectious diseases will also benefit from this model.”

Given their success in treating viruses such as Ebola, the use of antibodies to protect against influenza is of great interest to scientists. But while several influenza antibodies have progressed to clinical trials, the outcome in humans has been disappointing.

The latest study found that the 2-12C human antibody can neutralise the H1N1 2009 flu pandemic virus in pigs, and therefore provide protection. Both the amount of virus and signs of infection in the lungs were reduced in pigs that received treatment.

The success of this study in pigs suggests that antibody therapies have the potential to work in humans. It builds on previous research by Pirbright, which showed that pigs are good models for influenza vaccine studies.



Become a member or log in to add this story to your CPD history



Latest news | Careers | Events | Resources | Contact us | Terms and conditions | Data Protection and Privacy |Cookie policy | About us | Copyright
© 2024 Vision Media, all rights reserved. vnonline.co.uk is not responsible for the content of external websites.